Cat:GMP-h-MOG
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Product Details

Genemedi produces core diagnostic ingredients for test of Inflammation/autoimmune/inflammatory disease (MOG antibody disease) and related syndrome. GeneMedi offers paired diagnostics grade myelin oligodendrocyte glycoprotein (MOG) antibodies (monoclonal antibody, mab) and antigens for Inflammation/autoimmune/inflammatory disease (MOG antibody disease) rapid test kit of myelin oligodendrocyte glycoprotein (MOG) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Inflammation/autoimmune/inflammatory disease (MOG antibody disease ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Myelin oligodendrocyte glycoprotein antibody disorders (MOGAD) is an idiopathic, inflammatory, demyelinating disease of the central nervous system (CNS). MOG is a glycoprotein uniquely expressed in oligodendrocytes in the CNS. MOG antibodies were originally thought to be involved in multiple sclerosis (MS), but subsequent studies found it to be a distinct disease. MOGAD have many similarities to neuromyelitis optica but several studies have demonstrated they have unique clinical features, treatment response, and prognosis. MOGAD were initially identified in NMOSD antibody negative patients. Pathologically NMOSD is classified as am astrocytopathy, while MOGAD are classified as oligodendrogliopathies. The MOG antibody can distinguish a spectrum of autoimmune demyelinating diseases from multiple sclerosis (MS). Testing positive for the MOG antibody indicates that a patient doesn’t have classical MS. That’s important because diseases associated with the MOG antibody — as well as diseases associated with the water channel aquaporin-4 (AQP4) antibody, which was discovered at Mayo Clinic — are commonly misdiagnosed as MS. Yet some MS medications have been reported to worsen diseases that mimic MS. Which patients would benefit from this antibody testing? Any patient who suddenly presents with vision loss, significant disk edema or recurrent optic neuritis should consider testing for both MOG and AQP4 antibodies. Patients who have more than one episode of optic neuritis absolutely should have testing. An optic neuritis seems to be a very common presentation of MOG.

Product Description

Cat No. of Pruducts

GMP-h-MOG-Ag01:Recombinant Human MOG Protein

Product Name

Recombinant Human MOG Protein

Target

myelin oligodendrocyte glycoprotein

Alias of Target/Biomarker

BTN6, BTNL11, MOGIG2, NRCLP7

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

myelin oligodendrocyte glycoprotein (MOG) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MOG level test of Inflammation/autoimmune/inflammatory disease (MOG antibody disease) and related syndrome evaluation

Tag

His

Products description

Recombinant Human MOG Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-MOG-Ab01,GMP-h-MOG-Ab02:Anti-Human MOG mouse monoclonal antibody (mAb)

Product Name

Anti-Human MOG mouse monoclonal antibody (mAb)

Target

myelin oligodendrocyte glycoprotein (MOG)

Alias of Target/Biomarker

BTN6, BTNL11, MOGIG2, NRCLP7

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human myelin oligodendrocyte glycoprotein (MOG) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other myelin oligodendrocyte glycoprotein (MOG) antibodies in MOG level test of Inflammation/autoimmune/inflammatory disease (MOG antibody disease) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human MOG mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other myelin oligodendrocyte glycoprotein (MOG) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.