Genemedi produces core diagnostic ingredients for test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome. GeneMedi offers paired diagnostics grade Phospho-tau231 (p-tau231) antibodies (monoclonal antibody, mab) and antigens for Neurodegenerative diseases (Alzheimer Disease(AD)) rapid test kit of Phospho-tau231 (p-tau231) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Neurodegenerative diseases (Alzheimer Disease(AD) ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Alzheimer Disease(AD) Recent publications and meeting presentations bolster the evidence that upticks in p-tau181, p-tau217, and p-tau231 occur soon after Aβ begins to accumulate in the brain. That’s years before neurofibrillary tangles can be detected by PET, and decades before symptoms. Researchers predict these markers, which also distinguish AD from other forms of dementia, will lead to more robust tests than those based on Aβ, because of their larger dynamic range—phosphorylated fragments of tau climb by as much as 10-fold in the blood as AD progresses, whereas the Aβ42/40 ratio falls by about 15 percent at most.
Cat:GMP-h-p-tau231
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Product Details
Genemedi produces core diagnostic ingredients for test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome. GeneMedi offers paired diagnostics grade Phospho-tau231 (p-tau231) antibodies (monoclonal antibody, mab) and antigens for Neurodegenerative diseases (Alzheimer Disease(AD)) rapid test kit of Phospho-tau231 (p-tau231) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Neurodegenerative diseases (Alzheimer Disease(AD) ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.
Genemedi produces core diagnostic ingredients for test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome. GeneMedi offers paired diagnostics grade Phospho-tau231 (p-tau231) antibodies (monoclonal antibody, mab) and antigens for Neurodegenerative diseases (Alzheimer Disease(AD)) rapid test kit of Phospho-tau231 (p-tau231) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Neurodegenerative diseases (Alzheimer Disease(AD) ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Alzheimer Disease(AD)
Recent publications and meeting presentations bolster the evidence that upticks in p-tau181, p-tau217, and p-tau231 occur soon after Aβ begins to accumulate in the brain. That’s years before neurofibrillary tangles can be detected by PET, and decades before symptoms. Researchers predict these markers, which also distinguish AD from other forms of dementia, will lead to more robust tests than those based on Aβ, because of their larger dynamic range—phosphorylated fragments of tau climb by as much as 10-fold in the blood as AD progresses, whereas the Aβ42/40 ratio falls by about 15 percent at most.
Product Description
Cat No. of Pruducts
GMP-h-p-tau231-Ag01
Product Name
Recombinant human Human p-tau231 Protein
Target
Phospho-tau231
Alias of Target/Biomarker
Expression platform
synthesized
Isotypes
NA
Bioactivity validation
Phospho-tau231 (p-tau231) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau231 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Tag
Products description
Recombinant human Human p-tau231 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (HPLC)
Application
positive control,
ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -90℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts
GMP-h-p-tau231-Ab01,GMP-h-p-tau231-Ab02
Product Name
Anti-human Human p-tau231 mouse monoclonal antibody (mAb)
Target
Phospho-tau231
Alias of Target/Biomarker
DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform
Hybridoma
Isotypes
Mouse IgG
Bioactivity validation
Human Phospho-tau231 (p-tau231) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau231 (p-tau231) antibodies in p-tau231 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag
mFc
Products description
Anti-human Human p-tau231 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau231 (p-tau231) antibodies.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -91℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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