Cat:GMP-h-SAHH
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Product Details

Genemedi produces core diagnostic ingredients for test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome. GeneMedi offers paired diagnostics grade S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies (monoclonal antibody, mab) and antigens for Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) rapid test kit of S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.S-adenosylhomocysteine (AdoHcy) hydrolase (E.C.3.3.1.1) hydrolysis adenosine and homocysteine. In eukaryotes, this is the major route for disposal of the AdoHcy formed as a common product of each of many S-adenosylmethionine (AdoMet)-dependent methyltransferases. The reaction is reversible, but under normal conditions the removal of both adenosine and homocysteine is sufficiently rapid to maintain the flux in the direction of hydrolysis. AdoHcy is an inhibitor of many AdoMet-dependent methyltransferases. Thus, AdoHcy hydrolysis serves physiologically not only to sustain the flux of methionine sulfur toward cysteine, but is believed also to play a critical role in the regulation of biological methylations. The deficiency of AdoHcy leads to hypotonia with elevated serum creatine kinase and transaminases, prolonged prothrombin time and low albumin.

Product Description

Cat No. of Pruducts

GMP-h-SAHH-Ag01:Recombinant Human SAHH Protein

Product Name

Recombinant Human SAHH Protein

Target

S-adenosylhomocysteine (AdoHcy) hydrolase

Alias of Target/Biomarker

SAHH, adoHcyase

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation

Tag

His

Products description

Recombinant Human SAHH Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-SAHH-Ab01,GMP-h-SAHH-Ab02:Anti-Human SAHH mouse monoclonal antibody (mAb)

Product Name

Anti-Human SAHH mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

SAHH, adoHcyase

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies in SAHH level test of Metabolic diseases (S-adenosylhomocysteine (AdoHcy) hydrolase deficiency) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human SAHH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other S-adenosylhomocysteine (AdoHcy) hydrolase (SAHH) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

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