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Cat:GMP-h-sFlt-1
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Product Details
Genemedi produces core diagnostic ingredients for test of Cancer (ascular diseases and cancer) and related syndrome. GeneMedi offers paired diagnostics grade soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies (monoclonal antibody, mab) and antigens for Cancer (ascular diseases and cancer) rapid test kit of soluble vascular endothelial growth factor receptor-1 (sFlt-1) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cancer (ascular diseases and cancer ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Formation of new capillary blood vessels
from existing microvessels is called Angiogenesis, which plays a fundamental
role in many physiological and pathological processes such as embryo genesis,
wound healing and cancer. Angiogenic processes are controlled by a multitude of
positive and negative regulators. Vascular endothelial growth factor (VEGF) strongly
promotes angiogenesis. VEGF exerts multiple reactions by activating cell
membrane receptors with tyrosine kinase activity, such as VEGFR-1 (Flt-1),
VEGFR-2 (KDR/Flk-1) and VEGFR-3 (Flt-4) (4). The soluble form of the FLT-1
receptor, sFLT-1, is one of the efficient inhibitors of angiogenesis (10,12). The
sFLT-1 inhibits VEGF-driven migration of cancer cells. ?VEGF or sFLT-1 genes or their products have
been involved in the therapy of vascular diseases and cancer.
Product Description
Cat No. of Pruducts
GMP-h-sFlt-1-Ag01:Recombinant Human sFlt-1 Protein
Product Name
Recombinant Human sFlt-1 Protein
Target
soluble vascular endothelial growth factor receptor-1
Alias of Target/Biomarker
#N/A
Expression platform
E.coli
Isotypes
Recombinant Antigen
Bioactivity validation
soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation
Tag
His
Products description
Recombinant Human sFlt-1 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts
GMP-h-sFlt-1-Ab01,GMP-h-sFlt-1-Ab02:Anti-Human sFlt-1 mouse monoclonal antibody (mAb)
Product Name
Anti-Human sFlt-1 mouse monoclonal antibody (mAb)
Target
Alias of Target/Biomarker
#N/A
Expression platform
Hybridoma
Isotypes
Mouse IgG
Bioactivity validation
Human soluble vascular endothelial growth factor receptor-2 (sFlt-1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other soluble vascular endothelial growth factor receptor-2 (sFlt-1) antibodies in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation.
Tag
mFc
Products description
Anti-Human sFlt-1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other soluble vascular endothelial growth factor receptor-2 (sFlt-1) antibodies.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
