Cat:GMP-h-TNF
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Product Details

Genemedi produces core diagnostic ingredients for test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) and related syndrome. GeneMedi offers paired diagnostics grade tumor necrosis factor alpha (TNFα) antibodies (monoclonal antibody, mab) and antigens for Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) rapid test kit of tumor necrosis factor alpha (TNFα) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.The master pro-inflammatory cytokine, tumour necrosis factor (TNF), has been shown to modulate multiple signalling pathways, with wide-ranging downstream effects. TNF plays a vital role in the typical immune response through the regulation of a number of pathways encompassing an immediate inflammatory reaction with significant innate immune involvement as well as cellular activation with subsequent proliferation and programmed cell death or necrosis. As might be expected with such a broad spectrum of cellular effects and complex signalling pathways, TNF has also been implicated in a number of disease states, such as rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.

Product Description

Cat No. of Pruducts

GMP-h-TNF-Ag01:Recombinant Human TNF¦Á Protein

Product Name

Recombinant Human TNFα Protein

Target

tumor necrosis factor alpha

Alias of Target/Biomarker

DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha

Expression platform

E.coli

Isotypes

Recombinant Antigen

Bioactivity validation

tumor necrosis factor alpha (TNFα) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TNFα level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) and related syndrome evaluation

Tag

His

Products description

Recombinant Human TNFα Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-TNF-Ab01,GMP-h-TNF-Ab02:Anti-Human TNF¦Á mouse monoclonal antibody (mAb)

Product Name

Anti-Human TNFα mouse monoclonal antibody (mAb)

Target

Alias of Target/Biomarker

DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human tumor necrosis factor alpha (TNFα) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other tumor necrosis factor alpha (TNFα) antibodies in TNFα level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human TNFα mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other tumor necrosis factor alpha (TNFα) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.