GeneMedi’s AAV U6 expression vector is inserted with a promoter for human U6 to drive gene knockdown. You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry or luciferase.U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi.You can produce AAV paticle in 293T cell line in high titer using GeneMedi’s AAV expression vector (overexpression, shRNA or Crispr-cas9-gRNA) with GeneMedi’s serotypes-specific AAV Rep-Cap plasmids and AAV helper plasmid.