GeneMedi’s adenovirus U6 expression vector is inserted with a promoter for human U6 to drive gene knockdown. You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry or luciferase.
GeneMedi’s adenovirus CMV expression vector is inserted with a promoter for cytomegalovirus (CMV) to drive gene overexpression. You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry or luciferase.U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi.
The CMV promoter is a strong protomer driven broad expression in most tissues.You can easily produce a recombinant adenovirus (r-AdV) particle in HEK293 or HEK293A cell line in high titer using GeneMedi’s adenovirus Vector System including the adenovirus expression plasmids (overexpression, shRNA or Crispr-cas9-gRNA) and the adenovirus genome backbone plasmid.