human BCL2L12 Lentivirus plasmid
Cat:pGMLP000231
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP000231
Gene Name
BCL2L12
Product Name
human BCL2L12 Lentivirus plasmid
Accession Number
NM_138639
Gene ID
83596
Species
human
Product Type
Lentivirus plasmid
Insert Length
1005
Gene Alias
0
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Maker
GFP+PURO
Regulation
overexpression