human DCK Lentivirus plasmid

Cat:pGMLP000247
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLP000247 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLP000247

Gene Name

DCK

Product Name

human DCK Lentivirus plasmid

Accession Number

NM_000788

Gene ID

1633

Species

human

Product Type

Lentivirus plasmid

Insert Length

783

Gene Alias

0

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs.  Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents.  Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives.  DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

Maker

GFP+PURO

Regulation

overexpression