human LAT Lentivirus plasmid
Cat:pGMLP000495
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP000495
Gene Name
LAT
Product Name
human LAT Lentivirus plasmid
Accession Number
NM_001014987
Gene ID
27040
Species
human
Product Type
Lentivirus plasmid
Insert Length
702
Gene Alias
IMD52;LAT1;pp36
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression
