human FASLG Lentivirus plasmid

Cat:pGMLP000545
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLP000545

Gene Name

FASLG

Product Name

human FASLG Lentivirus plasmid

Accession Number

NM_000639

Gene ID

356

Species

human

Product Type

Lentivirus plasmid

Insert Length

846

Gene Alias

ALPS1B;APT1LG1;APTL;CD178;CD95-L;CD95L;FASL;TNFSF6;TNLG1A

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Maker

GFP+PURO

Regulation

overexpression