human LIN28A Lentivirus plasmid
Cat:pGMLV000061
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000061
Gene Name
LIN28A
Product Name
human LIN28A Lentivirus plasmid
Accession Number
NM_024674.5
Gene ID
79727
Species
human
Product Type
Lentivirus plasmid
Insert Length
630
Gene Alias
CSDD1;LIN-28;lin-28A;LIN28;ZCCHC1
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]
Maker
GFP+PURO
Regulation
overexpression
