mouse Dkk2 Lentivirus plasmid
Cat:pGMLV000083
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000083
Gene Name
Dkk2
Product Name
mouse Dkk2 Lentivirus plasmid
Accession Number
NM_020265.4
Gene ID
56811
Species
mouse
Product Type
Lentivirus plasmid
Insert Length
780
Gene Alias
Enables co-receptor binding activity. Involved in negative regulation of Wnt signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; eye; and genitourinary system. Orthologous to human DKK2 (dickkopf WNT signaling pathway inhibitor 2). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression
