rat Bckdk Lentivirus plasmid

Cat:pGMLV000092
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLV000092 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLV000092

Gene Name

Bckdk

Product Name

rat Bckdk Lentivirus plasmid

Accession Number

NM_019244.2

Gene ID

29603

Species

rat

Product Type

Lentivirus plasmid

Insert Length

1239

Gene Alias

Enables ATP binding activity; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; and protein serine/threonine kinase activity. Involved in branched-chain amino acid catabolic process; phosphorylation; and spermatogenesis. Part of mitochondrial alpha-ketoglutarate dehydrogenase complex. Used to study branched-chain keto acid dehydrogenase kinase deficiency and oligospermia. Human ortholog(s) of this gene implicated in branched-chain keto acid dehydrogenase kinase deficiency. Orthologous to human BCKDK (branched chain keto acid dehydrogenase kinase). [provided by Alliance of Genome Resources, Apr 2022]

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Maker

GFP+PURO

Regulation

overexpression