human TNFRSF10B Lentivirus plasmid
Cat:pGMLV000251
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000251
Gene Name
TNFRSF10B
Product Name
human TNFRSF10B Lentivirus plasmid
Accession Number
NM_003842.4
Gene ID
8795
Species
human
Product Type
Lentivirus plasmid
Insert Length
1323
Gene Alias
CD262;DR5;KILLER;KILLER/DR5;TRAIL-R2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9
Fluorescent Label
LUC+PURO
Fusion Tag
no tag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Maker
LUC+PURO
Regulation
overexpression
