rat Rnf8 Lentivirus plasmid
Cat:pGMLV000427
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000427
Gene Name
Rnf8
Product Name
rat Rnf8 Lentivirus plasmid
Accession Number
NM_001025727.1
Gene ID
361815
Species
rat
Product Type
Lentivirus plasmid
Insert Length
1464
Gene Alias
Predicted to enable several functions, including protein homodimerization activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including DNA metabolic process; protein ubiquitination; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in chromosome, telomeric region; cytoplasm; and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytosol; nucleus; and site of double-strand break. Orthologous to human RNF8 (ring finger protein 8). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Maker
GFP+PURO
Regulation
overexpression
