human SNCA Lentivirus plasmid
Cat:pGMLV000451
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000451
Gene Name
SNCA
Product Name
human SNCA Lentivirus plasmid
Accession Number
NM_000345.3
Gene ID
6622
Species
human
Product Type
Lentivirus plasmid
Insert Length
423
Gene Alias
NACP;PARK1;PARK4;PD1
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Maker
GFP+PURO
Regulation
overexpression
