human ALDH3A1 Lentivirus plasmid
Cat:pGMLV000478
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000478
Gene Name
ALDH3A1
Product Name
human ALDH3A1 Lentivirus plasmid
Accession Number
NM_001135168.1
Gene ID
218
Species
human
Product Type
Lentivirus plasmid
Insert Length
1362
Gene Alias
ALDH3;ALDHIII
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Maker
GFP+PURO
Regulation
overexpression