Norway rat Uchl1 Lentivirus plasmid
Cat:pGMLV000740
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLV000740
Gene Name
Uchl1
Product Name
Norway rat Uchl1 Lentivirus plasmid
Accession Number
NM_017237.3
Gene ID
29545
Species
Norway rat
Product Type
Lentivirus plasmid
Insert Length
672
Gene Alias
Predicted to enable several functions, including alpha-2A adrenergic receptor binding activity; cysteine-type peptidase activity; and ubiquitin protein ligase binding activity. Involved in sensory perception of pain and ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including neuron projection terminus; neuronal cell body; and nucleoplasm. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Biomarker of retinal disease. Human ortholog(s) of this gene implicated in Alzheimer’s disease; Parkinson’s disease; and hereditary spastic paraplegia. Orthologous to human UCHL1 (ubiquitin C-terminal hydrolase L1). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP-PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
Maker
GFP-PURO
Regulation
overexpression