Antibodies and antigens for small molecule Metabolites/Chemicals-in Vitro diagnostics (IVD)

Table of Contents

Products Introduction

The small molecule Metabolite/Chemical entries, both water-soluble and lipid-soluble, are intended to be used for application in multiple disease detection, prognosis prediction, and metabolomics. Diagnostic chemicals and metabolites, including small peptides, are important biomarkers for evaluating and predicting physiological and Pathological conditions.

For instance, age-related bone loss, leading to osteoporosis, is accelerated by impaired calcium intake and low levels of 25-hydroxyvitamin D (25(OH)D). Reduced production of a significant precursor of vitamin D in the skin and reduced synthesis of active vitamin D metabolite (1,25(OH)2D) in the kidneys cause lower calcium absorption, subsequently, enhanced bone resorption. The calcium-related marker, 25-OH-VD, is useful to monitor the efficacy of anti-osteoporosis treatments and to predict fracture risk.

Fig1. Schematic of calcium homeostasis. The solid line represents stimulatory interaction, the dashed line indicates negative feedback. (LuSong, Calcium and Bone Metabolism IndicesAuthor links open overlay panel)

Product List

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Cat No.of Antigen
Bioactivity validation of Antigen
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Bioactivity validation of Antibodies
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Human
Human
25 hydroxyvitamin D (25-OH-(VD3+VD2))
GMP-SMT-25-OH-(VD3+VD2)Ag01:BSA-25 hydroxyvitamin D (25-OH-(VD3+VD2)) ;GMP-SMT-25-OH-(VD3+VD2)Ag02: OVA-25 hydroxyvitamin D (25-OH-(VD3+VD2))
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-25 hydroxyvitamin D (25-OH-(VD3+VD2)), 25 hydroxyvitamin D (25-OH-(VD3+VD2)) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in 25-OH-(VD3+VD2) level test of Metabolic diseases (bone fracture, coronary heart disease, cancer, and all-cause mortality) and related syndrome evaluation.
GMP-SMT-25-OH-(VD3+VD2)-Ab01
Anti-25 hydroxyvitamin D (25-OH-(VD3+VD2)) mouse monoclonal antibody (mAb)
Human 25 hydroxyvitamin D (25-OH-(VD3+VD2)) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in 25-OH-(VD3+VD2) level test of Metabolic diseases (bone fracture, coronary heart disease, cancer, and all-cause mortality) and related syndrome evaluation.
Human
25-hydroxy (OH) Vitamin (25-OH-VD)
GMP-SMT-25-OH-VDAg01:BSA-25-hydroxy (OH) Vitamin (25-OH-VD) ;GMP-SMT-25-OH-VDAg02: OVA-25-hydroxy (OH) Vitamin (25-OH-VD)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-25-hydroxy (OH) Vitamin (25-OH-VD), 25-hydroxy (OH) Vitamin (25-OH-VD) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in 25-OH-VD level test of Metabolic diseases (osteoporosis?and?rickets) and related syndrome evaluation.
GMP-SMT-25-OH-VD-Ab01
Anti-25-hydroxy (OH) Vitamin (25-OH-VD) mouse monoclonal antibody (mAb)
Human 25-hydroxy (OH) Vitamin (25-OH-VD) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in 25-OH-VD level test of Metabolic diseases (osteoporosis and rickets) and related syndrome evaluation.
Human
GMP-SMT-Bisphenol-AAg01:BSA-Bisphenol A ;GMP-SMT-Bisphenol-AAg02: OVA-Bisphenol A
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Bisphenol A, Bisphenol A antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Bisphenol A level test of Hormone disorders (Toxicity, mutagen and carcinogen) and related syndrome evaluation.
GMP-SMT-Bisphenol-A-Ab01
Anti-Bisphenol A mouse monoclonal antibody (mAb)
Human Bisphenol A binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Bisphenol A level test of Hormone disorders (Toxicity, mutagen and carcinogen) and related syndrome evaluation.
Human
GMP-SMT-CalcitoninAg01:BSA-Calcitonin ;GMP-SMT-CalcitoninAg02: OVA-Calcitonin
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Calcitonin, Calcitonin antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Calcitonin level test of Hormone disorders (thyroid cancer) and related syndrome evaluation.
GMP-SMT-Calcitonin-Ab01
Anti-Calcitonin mouse monoclonal antibody (mAb)
Human Calcitonin binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Calcitonin level test of Hormone disorders (thyroid cancer) and related syndrome evaluation.
Human
cyclic citrullinated peptide (CCP)
GMP-SMT-CCPAg01:BSA-cyclic citrullinated peptide (CCP) ;GMP-SMT-CCPAg02: OVA-cyclic citrullinated peptide (CCP)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-cyclic citrullinated peptide (CCP), cyclic citrullinated peptide (CCP) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in CCP level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis) and related syndrome evaluation.
GMP-SMT-CCP-Ab01
Anti-cyclic citrullinated peptide (CCP) mouse monoclonal antibody (mAb)
Human cyclic citrullinated peptide (CCP) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in CCP level test of Inflammation/autoimmune/inflammatory disease (rheumatoid arthritis) and related syndrome evaluation.
Human
Human
Cholyglycine (CG)
GMP-SMT-CGAg01:BSA-Cholyglycine (CG) ;GMP-SMT-CGAg02: OVA-Cholyglycine (CG)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Cholyglycine (CG), Cholyglycine (CG) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in CG level test of Liver diseases (liver cirrhosis or obstructive liver disease) and related syndrome evaluation.
GMP-SMT-CG-Ab01
Anti-Cholyglycine (CG) mouse monoclonal antibody (mAb)
Human Cholyglycine (CG) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in CG level test of Liver diseases (liver cirrhosis or obstructive liver disease) and related syndrome evaluation.
Human
Human
deoxycholic acid (cholanoic acid)
GMP-SMT-cholanoic acidAg01:BSA-deoxycholic acid (cholanoic acid) ;GMP-SMT-cholanoic acidAg02: OVA-deoxycholic acid (cholanoic acid)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-deoxycholic acid (cholanoic acid), deoxycholic acid (cholanoic acid) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in cholanoic acid level test of Liver diseases (liver cirrhosis, chronic kidney disease, vascular calcification, vasculature toxicity) and related syndrome evaluation.
GMP-SMT-cholanoic acid-Ab01
Anti-deoxycholic acid (cholanoic acid) mouse monoclonal antibody (mAb)
Human deoxycholic acid (cholanoic acid) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in cholanoic acid level test of Liver diseases (liver cirrhosis, chronic kidney disease, vascular calcification, vasculature toxicity) and related syndrome evaluation.
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GM-Solution for chemicals diagnostics and small molecule metabolites detection in the human body

GeneMedi Diagnostics Unit (GDU) is developing dynamic solutions for chemicals & metabolites immuno-assay-based rapid detection to improve application sensitivity, specificity, stability, and flexibility. Powered by G-SMSTM platform, GDU’s better small molecule biosensors contribute to small molecule metabolites’ rapid test application including ELISA test, competitive ELISA, Lateral flow immunoassay (LFA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Antigens for diagnostic chemicals and small molecule metabolites

The small molecule is hapten that hardly induces body immuno-reaction. To me both small molecule diagnosis and small molecule antibody discovery, the hapten-carrier conjugates are more applicable. The hapten-carrier conjugates for diagnostics chemicals and small molecule metabolites are also available in GDU products.

About G-SMS™

GeneMedi’s Small Molecule bioSensors discovery platform for more sensitive, specific and flexible small molecule detection.

Small molecule antigen & antibody list

Competitive immunoassay-validated anti-Hapten(small molecules, chemicals) antibody against hapten (small molecules, chemicals) and hapten-carrier conjugated competitive antigens(Carrier-coupled antigen,immunogen,hapten-carrier conjugates, BSA-conjugated, OVA-conjugated).

The anti-Hapten antibodies against haptens had been validated with our hapten-carrier conjugates via competitive ELISA test.

GeneMedi offers paired anti-small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.) antibodies (monoclonal antibody, mab) and small molecules competitive antigens (Carrier-coupled antigen, immunogen, hapten-carrier conjugates, BSA-conjugated, OVA-conjugated) for the rapid test and diagnostics kit of Growth Promoters, Toxic Heavy Metal, Myotoxins,Nutritions, Food Safety, Pesticides, Drugs of Abuse, Allergen, Antibiotics, Agricultural, Water Contamination and so on.

All our anti-chemicals antibodies and small molecules hapten-carrier conjugates antigens (BSA-conjugated, OVA-conjugated)are suitable for in competitive ELISA, Lateral flow immunoassay (LFIA) and other immunoassays in dignostics and rapid test kit. The carrier-coupled antigens of small molecules can act as immunogens.

Genemedi supplies Small Molecule Diagnostic for a wide selection of choices (please see below).