Antibodies and antigens for small molecule Metabolites/Chemicals-in Vitro diagnostics (IVD)

Table of Contents

Products Introduction

The small molecule Metabolite/Chemical entries, both water-soluble and lipid-soluble, are intended to be used for application in multiple disease detection, prognosis prediction, and metabolomics. Diagnostic chemicals and metabolites, including small peptides, are important biomarkers for evaluating and predicting physiological and Pathological conditions.

For instance, age-related bone loss, leading to osteoporosis, is accelerated by impaired calcium intake and low levels of 25-hydroxyvitamin D (25(OH)D). Reduced production of a significant precursor of vitamin D in the skin and reduced synthesis of active vitamin D metabolite (1,25(OH)2D) in the kidneys cause lower calcium absorption, subsequently, enhanced bone resorption. The calcium-related marker, 25-OH-VD, is useful to monitor the efficacy of anti-osteoporosis treatments and to predict fracture risk.

Fig1. Schematic of calcium homeostasis. The solid line represents stimulatory interaction, the dashed line indicates negative feedback. (LuSong, Calcium and Bone Metabolism IndicesAuthor links open overlay panel)

Product List

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Bioactivity validation of Antigen
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Bioactivity validation of Antibodies
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Human
Human
GMP-SMT-CortisolAg01:BSA-Cortisol ;GMP-SMT-CortisolAg02: OVA-Cortisol
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Cortisol, Cortisol antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Cortisol level test of Hormone disorders (adrenal gland disorder) and related syndrome evaluation.
GMP-SMT-Cortisol-Ab01
Anti-Cortisol mouse monoclonal antibody (mAb)
Human Cortisol binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Cortisol level test of Hormone disorders (adrenal gland disorder) and related syndrome evaluation.
Human
GMP-SMT-DES-HESAg01:BSA-Diethylstilbestrol/Hexestrol (DES/HES) ;GMP-SMT-DES-HESAg02: OVA-Diethylstilbestrol/Hexestrol (DES/HES)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Diethylstilbestrol/Hexestrol (DES/HES), Diethylstilbestrol/Hexestrol (DES/HES) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in DES/HES level test of Hormone disorders (Food safety) and related syndrome evaluation.
GMP-SMT-DES-HES-Ab01
Anti-Diethylstilbestrol/Hexestrol (DES/HES) mouse monoclonal antibody (mAb)
Human Diethylstilbestrol/Hexestrol (DES/HES) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in DES/HES level test of Hormone disorders (Food safety) and related syndrome evaluation.
Human
GMP-SMT-DEXAg01:BSA-Dexamethasone (DEX) ;GMP-SMT-DEXAg02: OVA-Dexamethasone (DEX)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Dexamethasone (DEX), Dexamethasone (DEX) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in DEX level test of Hormone disorders (Cushing's syndrome) and related syndrome evaluation.
GMP-SMT-DEX-Ab01
Anti-Dexamethasone (DEX) mouse monoclonal antibody (mAb)
Human Dexamethasone (DEX) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in DEX level test of Hormone disorders (Cushing's syndrome) and related syndrome evaluation.
Human
dehydroepiandrosterone (DHEA)
GMP-SMT-DHEAAg01:BSA-dehydroepiandrosterone (DHEA) ;GMP-SMT-DHEAAg02: OVA-dehydroepiandrosterone (DHEA)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-dehydroepiandrosterone (DHEA), dehydroepiandrosterone (DHEA) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in DHEA level test of Hormone disorders (Hormone disorders) and related syndrome evaluation.
GMP-SMT-DHEA-Ab01
Anti-dehydroepiandrosterone (DHEA) mouse monoclonal antibody (mAb)
Human dehydroepiandrosterone (DHEA) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in DHEA level test of Hormone disorders (Hormone disorders) and related syndrome evaluation.
Human
Human
digoxigenin (Digoxin)
GMP-SMT-DigoxinAg01:BSA-digoxigenin (Digoxin) ;GMP-SMT-DigoxinAg02: OVA-digoxigenin (Digoxin)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-digoxigenin (Digoxin), digoxigenin (Digoxin) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Digoxin level test of Cardiovascular disease and related syndrome evaluation.
GMP-SMT-Digoxin-Ab01
Anti-digoxigenin (Digoxin) mouse monoclonal antibody (mAb)
Human digoxigenin (Digoxin) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Digoxin level test of Cardiovascular disease and related syndrome evaluation.
Human
Human
GMP-SMT-E1Ag01:BSA-Estrone (E1) ;GMP-SMT-E1Ag02: OVA-Estrone (E1)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Estrone (E1), Estrone (E1) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in E1 level test of Hormone disorders (irregular bleeding, fatigue or mood swings) and related syndrome evaluation.
GMP-SMT-E1-Ab01
Anti-Estrone (E1) mouse monoclonal antibody (mAb)
Human Estrone (E1) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in E1 level test of Hormone disorders (irregular bleeding, fatigue or mood swings) and related syndrome evaluation.
Human
GMP-SMT-E2-E3Ag01:BSA-Estradiol (E2/E3) ;GMP-SMT-E2-E3Ag02: OVA-Estradiol (E2/E3)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Estradiol (E2/E3), Estradiol (E2/E3) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in E2/E3 level test of Hormone disorders (Fertility) and related syndrome evaluation.
GMP-SMT-E2-E3-Ab01
Anti-Estradiol (E2/E3) mouse monoclonal antibody (mAb)
Human Estradiol (E2/E3) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in E2/E3 level test of Hormone disorders (Fertility) and related syndrome evaluation.
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GM-Solution for chemicals diagnostics and small molecule metabolites detection in the human body

GeneMedi Diagnostics Unit (GDU) is developing dynamic solutions for chemicals & metabolites immuno-assay-based rapid detection to improve application sensitivity, specificity, stability, and flexibility. Powered by G-SMSTM platform, GDU’s better small molecule biosensors contribute to small molecule metabolites’ rapid test application including ELISA test, competitive ELISA, Lateral flow immunoassay (LFA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Antigens for diagnostic chemicals and small molecule metabolites

The small molecule is hapten that hardly induces body immuno-reaction. To me both small molecule diagnosis and small molecule antibody discovery, the hapten-carrier conjugates are more applicable. The hapten-carrier conjugates for diagnostics chemicals and small molecule metabolites are also available in GDU products.

About G-SMS™

GeneMedi’s Small Molecule bioSensors discovery platform for more sensitive, specific and flexible small molecule detection.

Small molecule antigen & antibody list

Competitive immunoassay-validated anti-Hapten(small molecules, chemicals) antibody against hapten (small molecules, chemicals) and hapten-carrier conjugated competitive antigens(Carrier-coupled antigen,immunogen,hapten-carrier conjugates, BSA-conjugated, OVA-conjugated).

The anti-Hapten antibodies against haptens had been validated with our hapten-carrier conjugates via competitive ELISA test.

GeneMedi offers paired anti-small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.) antibodies (monoclonal antibody, mab) and small molecules competitive antigens (Carrier-coupled antigen, immunogen, hapten-carrier conjugates, BSA-conjugated, OVA-conjugated) for the rapid test and diagnostics kit of Growth Promoters, Toxic Heavy Metal, Myotoxins,Nutritions, Food Safety, Pesticides, Drugs of Abuse, Allergen, Antibiotics, Agricultural, Water Contamination and so on.

All our anti-chemicals antibodies and small molecules hapten-carrier conjugates antigens (BSA-conjugated, OVA-conjugated)are suitable for in competitive ELISA, Lateral flow immunoassay (LFIA) and other immunoassays in dignostics and rapid test kit. The carrier-coupled antigens of small molecules can act as immunogens.

Genemedi supplies Small Molecule Diagnostic for a wide selection of choices (please see below).