Antibodies and antigens for small molecule Metabolites/Chemicals-in Vitro diagnostics (IVD)

Table of Contents

Products Introduction

The small molecule Metabolite/Chemical entries, both water-soluble and lipid-soluble, are intended to be used for application in multiple disease detection, prognosis prediction, and metabolomics. Diagnostic chemicals and metabolites, including small peptides, are important biomarkers for evaluating and predicting physiological and Pathological conditions.

For instance, age-related bone loss, leading to osteoporosis, is accelerated by impaired calcium intake and low levels of 25-hydroxyvitamin D (25(OH)D). Reduced production of a significant precursor of vitamin D in the skin and reduced synthesis of active vitamin D metabolite (1,25(OH)2D) in the kidneys cause lower calcium absorption, subsequently, enhanced bone resorption. The calcium-related marker, 25-OH-VD, is useful to monitor the efficacy of anti-osteoporosis treatments and to predict fracture risk.

Fig1. Schematic of calcium homeostasis. The solid line represents stimulatory interaction, the dashed line indicates negative feedback. (LuSong, Calcium and Bone Metabolism IndicesAuthor links open overlay panel)

Product List

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Biomarker
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Bioactivity validation of Antigen
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Bioactivity validation of Antibodies
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Human
acetaminophen (Paracetamol)
GMP-SMT-ParacetamolAg01:BSA-acetaminophen (Paracetamol) ;GMP-SMT-ParacetamolAg02: OVA-acetaminophen (Paracetamol)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-acetaminophen (Paracetamol), acetaminophen (Paracetamol) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Paracetamol level test of Pain (hepatotoxicity) and related syndrome evaluation.
GMP-SMT-Paracetamol-Ab01
Anti-acetaminophen (Paracetamol) mouse monoclonal antibody (mAb)
Human acetaminophen (Paracetamol) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Paracetamol level test of Pain (hepatotoxicity) and related syndrome evaluation.
Human
Human
GMP-SMT-PGAg01:BSA-Prostaglandin (PG) ;GMP-SMT-PGAg02: OVA-Prostaglandin (PG)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Prostaglandin (PG), Prostaglandin (PG) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in PG level test of Hormone disorders (acute inflammation) and related syndrome evaluation.
GMP-SMT-PG-Ab01
Anti-Prostaglandin (PG) mouse monoclonal antibody (mAb)
Human Prostaglandin (PG) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in PG level test of Hormone disorders (acute inflammation) and related syndrome evaluation.
Human
GMP-SMT-ProgesteroneAg01:BSA-Progesterone ;GMP-SMT-ProgesteroneAg02: OVA-Progesterone
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Progesterone, Progesterone antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Progesterone level test of Hormone disorders (fertility) and related syndrome evaluation.
GMP-SMT-Progesterone-Ab01
Anti-Progesterone mouse monoclonal antibody (mAb)
Human Progesterone binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Progesterone level test of Hormone disorders (fertility) and related syndrome evaluation.
Human
GMP-SMT-ProlactinAg01:BSA-Prolactin ;GMP-SMT-ProlactinAg02: OVA-Prolactin
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Prolactin, Prolactin antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in Prolactin level test of Hormone disorders (fertility) and related syndrome evaluation.
GMP-SMT-Prolactin-Ab01
Anti-Prolactin mouse monoclonal antibody (mAb)
Human Prolactin binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in Prolactin level test of Hormone disorders (fertility) and related syndrome evaluation.
Human
aldosterone (RAA/Aldo)
GMP-SMT-RAA-AldoAg01:BSA-aldosterone (RAA/Aldo) ;GMP-SMT-RAA-AldoAg02:OVA-aldosterone (RAA/Aldo)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-aldosterone (RAA/Aldo), aldosterone (RAA/Aldo) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in RAA/Aldo level test of Cardiovascular disease (Hypertension, blood pressure, hyperaldosteronism, renal artery stenosis (narrowing of the renal artery), congestive heart failure, cirrhosis, some kidney diseases (e.g., nephrotic syndrome).) and related syndrome evaluation.
GMP-SMT-RAA-Aldo-Ab01
Anti-aldosterone (RAA/Aldo) mouse monoclonal antibody (mAb)
Human aldosterone (RAA/Aldo) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in RAA/Aldo level test of Cardiovascular disease (Hypertension, blood pressure, hyperaldosteronism, renal artery stenosis (narrowing of the renal artery), congestive heart failure, cirrhosis, some kidney diseases (e.g., nephrotic syndrome).) and related syndrome evaluation.
Human
Human
GMP-SMT-RBP4Ag01:BSA-Retinol binding protein 4 (RBP4) ;GMP-SMT-RBP4Ag02: OVA-Retinol binding protein 4 (RBP4)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Retinol binding protein 4 (RBP4), Retinol binding protein 4 (RBP4) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in RBP4 level test of Metabolic diseases (obesity, type 2 diabetes, metabolic syndrome, and cardiovascular diseases) and related syndrome evaluation.
GMP-SMT-RBP4-Ab01
Anti-Retinol binding protein 4 (RBP4) mouse monoclonal antibody (mAb)
Human Retinol binding protein 4 (RBP4) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in RBP4 level test of Metabolic diseases (obesity, type 2 diabetes, metabolic syndrome, and cardiovascular diseases) and related syndrome evaluation.
Human
Reverse triiodothyronine (rT3)
GMP-SMT-rT3Ag01:BSA-Reverse triiodothyronine (rT3) ;GMP-SMT-rT3Ag02: OVA-Reverse triiodothyronine (rT3)
Competitive immunoassay-validated hapten-carrier conjugates BSA-& OVA-Reverse triiodothyronine (rT3), Reverse triiodothyronine (rT3) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays as control material in rT3 level test of Thyroid diseases (stress?) and related syndrome evaluation.
GMP-SMT-rT3-Ab01
Anti-Reverse triiodothyronine (rT3) mouse monoclonal antibody (mAb)
Human Reverse triiodothyronine (rT3) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in rT3 level test of Thyroid diseases (stress) and related syndrome evaluation.
Human
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GM-Solution for chemicals diagnostics and small molecule metabolites detection in the human body

GeneMedi Diagnostics Unit (GDU) is developing dynamic solutions for chemicals & metabolites immuno-assay-based rapid detection to improve application sensitivity, specificity, stability, and flexibility. Powered by G-SMSTM platform, GDU’s better small molecule biosensors contribute to small molecule metabolites’ rapid test application including ELISA test, competitive ELISA, Lateral flow immunoassay (LFA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Antigens for diagnostic chemicals and small molecule metabolites

The small molecule is hapten that hardly induces body immuno-reaction. To me both small molecule diagnosis and small molecule antibody discovery, the hapten-carrier conjugates are more applicable. The hapten-carrier conjugates for diagnostics chemicals and small molecule metabolites are also available in GDU products.

About G-SMS™

GeneMedi’s Small Molecule bioSensors discovery platform for more sensitive, specific and flexible small molecule detection.

Small molecule antigen & antibody list

Competitive immunoassay-validated anti-Hapten(small molecules, chemicals) antibody against hapten (small molecules, chemicals) and hapten-carrier conjugated competitive antigens(Carrier-coupled antigen,immunogen,hapten-carrier conjugates, BSA-conjugated, OVA-conjugated).

The anti-Hapten antibodies against haptens had been validated with our hapten-carrier conjugates via competitive ELISA test.

GeneMedi offers paired anti-small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.) antibodies (monoclonal antibody, mab) and small molecules competitive antigens (Carrier-coupled antigen, immunogen, hapten-carrier conjugates, BSA-conjugated, OVA-conjugated) for the rapid test and diagnostics kit of Growth Promoters, Toxic Heavy Metal, Myotoxins,Nutritions, Food Safety, Pesticides, Drugs of Abuse, Allergen, Antibiotics, Agricultural, Water Contamination and so on.

All our anti-chemicals antibodies and small molecules hapten-carrier conjugates antigens (BSA-conjugated, OVA-conjugated)are suitable for in competitive ELISA, Lateral flow immunoassay (LFIA) and other immunoassays in dignostics and rapid test kit. The carrier-coupled antigens of small molecules can act as immunogens.

Genemedi supplies Small Molecule Diagnostic for a wide selection of choices (please see below).