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The Landscape of Neutralizing antibodies (NAb): Production, Mechanisms of Action (MOA), FDA approved-antibodies, and Functional assay

Table of Contents FDA approved neutralizing antibodies (NAb) and our products 1. SARS-CoV-2 neutralizing antibodies (NAb) SARS-CoV-2, the novel coronavirus responsible for the ongoing COVID-19 pandemic, has been spreading rampantly. The global scientific community has responded rapidly to understand immune correlates of protection to develop vaccines and immunotherapeutic against the virus. The RBD of spike […]

Tandem VHH/ Nanobody: Structure, Production, Application and Products

Since 1975, monoclonal antibodies have been successfully used for the diagnosis and therapeutics. In 1993, heavy-chain-only antibodies which bind to antigens was discovered in camelids. The variable domain of heavy chain antibody (VHH) was called as nanobodies and it was anticipated as the better therapeutic antibodies in future due to its high stability, refoldability, and manipulable characteristics. […]

Bispecific antibodies: formats, applications and products

Table of Contents Products Introduction Bispecific antibodies (BsAbs) are antibodies with two binding sites directed at two different antigens or two different epitopes on the same antigen. A bispecific antibody (bsAb) is designed and manufactured—through genetic recombination, chemical conjugation, or quadromas—to contain two target‐binding units in one antibody‐based molecule, whereby each unit independently recognizes its […]