Diagnostic recombinant Alpha-1-microglobulin (A1M) antigens (recombinant Alpha-1-microglobulin (A1M) ) protein) for kidney function (renal damages)A1M detection in positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Product Details
Urinary microproteins are becoming increasingly important in clinical diagnostics. They can contribute in the non-invasive early detection of renal abnormalities and the differentiation of various nephrological and urological pathologies.
Alpha-1-microglobulin (A1M, α1-microglobulin, sometimes also called Protein HC) is a microglobulin, a small globular protein. It is found in all vertebrates, including humans, and is distributed in blood plasma and extravascular tissues of all organs. It is synthesized in most cells of the body, but mainly in the liver from a gene that codes for the alpha-1-microglobulin/bikunin precursor.
A1M can be used as an indicator of proteinuria. The test can be regarded as positive when the ratio of A1M (in milligrams) and creatinine in millimoles in the urine is over 0.7 mg/mmol.
A test for preeclampsia, where A1M serves as the diagnostic marker, has been proposed. It is based upon the fact that oxidative stress in the placenta tissue triggers the endogenous synthesis and plasma concentration of the protein.Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.
Genemedi produces core diagnostic ingredients for test of kidney function (renal damages) and related syndrome.
GeneMedi offers paired diagnostics grade Alpha-1-microglobulin (A1M) antibodies (monoclonal antibody, mab) and Alpha-1-microglobulin (A1M) antigens for kidney function (renal damages) rapid test kit of Alpha-1-microglobulin (A1M) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.GeneMedi offers paired diagnostics grade Alpha-1-microglobulin (A1M) antibodies (monoclonal antibody, mab) and Alpha-1-microglobulin (A1M) antigens for kidney function (renal damages) rapid test kit of Alpha-1-microglobulin (A1M) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for kidney function (renal damages) test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of kidney function (renal damages).
Product Description
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Antigen & Antibody Name
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Expression platform
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Isotypes
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Bioactivity validation
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Tag
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Products description
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Purity
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Application
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Formulation
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Cat No.
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GMP-A1M-Ag
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Product Name
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Recombinant human Human A1M Protein
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Expression platform
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E.coli
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Isotypes
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Recombinant Antigen
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Bioactivity validation
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Alpha-1-microglobulin (A1M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation
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Tag
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His
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Products description
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Recombinant human Human A1M Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
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Purity
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Purity: ≥95% (SDS-PAGE)
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Application
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Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
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Formulation
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Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
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Storage
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Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma.
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.
Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.
GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis,Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2),Cytomegalovirus (CMV),rubella virus,toxoplasma gondii and so on.
All the antibodies of inflammation and CRS test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibody can act as a capture antibody and detection antibody.
