Diagnostic Heat shock proteins 90-alpha (HSP90α) antibodies (anti-Heat shock proteins 90-alpha, anti-HSP90α) for Tumor/Cancer HSP90α detection in ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Product Details
The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.Genemedi produces core diagnostic ingredients for test of Tumor/Cancer and related syndrome.
GeneMedi offers paired diagnostics grade Heat shock proteins 90-alpha (HSP90α) ) antibodies (monoclonal antibody, mab) and Heat shock proteins 90-alpha (HSP90α) ) antigens for Tumor/Cancer rapid test kit of Heat shock proteins 90-alpha (HSP90α) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
All the antibodies and antigens for Tumor/Cancer test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of Tumor/Cancer.
Product Description
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Antigen & Antibody Name
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Anti-human Human HSP90α mouse monoclonal antibody (mAb)
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Expression platform
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Hybridoma
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Isotypes
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Mouse IgG
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Bioactivity validation
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Human Heat shock proteins 90-alpha (HSP90α) (HSP90α) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies in HSP90α level test of Cancer (renal cancer, liver cancer and breast cancer) and related syndrome evaluation.
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Tag
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mFc
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Products description
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Anti-human Human HSP90α mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Heat shock proteins 90-alpha (HSP90α) (HSP90α) antibodies.
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Purity
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Purity: ≥95% (SDS-PAGE)
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Application
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ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
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Formulation
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Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
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Storage
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Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No.
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GMP-HSP90-Ab
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Product Name
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Expression platform
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Bioactivity validation
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Products description
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Purity
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Formulation
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Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma.
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.
Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.
GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis,Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2),Cytomegalovirus (CMV),rubella virus,toxoplasma gondii and so on.
All the antibodies of inflammation and CRS test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibody can act as a capture antibody and detection antibody.
