Diagnostic recombinant Pepsinogen II (PG II) antigens (recombinant Pepsinogen II (PG II) ) protein) for gastric disease PG II detection in positive control, ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Product Details
Pepsinogen II(PGII) – The Pepsinogens are gastric acid protease zymogens. They are divided into two distinct immunochemical groups. Pepsinogen I and II. Pepsinogen II is one of 4 aspartic proteinases: PG I, PG II, Cathepsin E and D. Pepsinogen II is produced primarily in the Oxyntic gland mucosa of the stomach, the gastric antrum and the duodenum. It is secreted mainly into the gastric lumen and into circulation. Pepsinogen II has little or no biological activity but in acid is converted to the active enzyme Pepsin which exhibits proteolytic actions. Unlike Pepsinogen I, Pepsinogen II is not normally found in the urine. Patients with pernicious anemia have low to non-detectable levels of Pepsinogen I but normal levels of Pepsinogen II. Pepsinogen II levels are slightly elevated in gastric ulcer. Patients with Zollinger-Ellison’s syndrome exhibit greatly elevated levels. Genemedi produces core diagnostic ingredients for test of gastric disease and related syndrome. GeneMedi offers paired diagnostics grade Pepsinogen II (PG II) antibodies (monoclonal antibody, mab) and Pepsinogen II (PG II) antigens for gastric disease rapid test kit of Pepsinogen II (PG II) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.All the antibodies and antigens for gastric disease test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of gastric disease.
Product Description
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Antigen & Antibody Name
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Expression platform
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Isotypes
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Bioactivity validation
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Tag
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Products description
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Purity
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Application
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Formulation
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Storage
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Cat No.
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GMP-PG-II-Ag
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Product Name
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Recombinant human Human PG II Protein
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Expression platform
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E.coli
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Isotypes
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Recombinant Antigen
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Bioactivity validation
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Pepsinogen II (PG II) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation
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Tag
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His
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Products description
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Recombinant human Human PG II Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
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Purity
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Purity: ≥95% (SDS-PAGE)
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Application
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Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
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Formulation
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Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
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Storage
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Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma.
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.
Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.
GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis,Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2),Cytomegalovirus (CMV),rubella virus,toxoplasma gondii and so on.
All the antibodies of inflammation and CRS test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibody can act as a capture antibody and detection antibody.
