Diagnostic Procollagen III N-terminal peptide (PIIINP) antibodies (anti-Procollagen III N-terminal peptide, anti-PIIINP) for Liver Diseases/Fibrosis PIIINP detection in ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Product Details
Procollagen III N-terminal peptide (PIIINP), also known as Type III procollagen peptide, is a serum marker of collagen turnover and is used to assess hepatic fibrosis in patients on long-term Methotrexate.
Background: PIIINP is the amino terminal peptide of type III procollagen, released from the precursor peptide during the synthesis and deposition of type III collagen. PIIINP in the serum can be derived from the synthesis of new type III collagen or from the degradation of existing type III collagen fibrils. There is evidence that serum PIIINP measurement is an effective non-invasive test for the detection and monitoring of Methotrexate-induced liver fibrosis and cirrhosis, and serial measurements may reduce the need for liver biopsy. Dermatology patients with repeated normal levels of PIIINP are very unlikely to have significant liver damage from fibrosis or cirrhosis. Conversely a high serum PIIINP or series of high values may indicate that a liver biopsy is required and in some cases, that Methotrexate should be withdrawn.
Note that PIIINP can be raised following bone fracture and also in rheumatology patients as it can be falsely elevated in inflammatory arthritis.Genemedi produces core diagnostic ingredients for test of Liver Diseases/Fibrosis and related syndrome.
GeneMedi offers paired diagnostics grade Procollagen III N-terminal peptide (PIIINP) ) antibodies (monoclonal antibody, mab) and Procollagen III N-terminal peptide (PIIINP) ) antigens for Liver Diseases/Fibrosis rapid test kit of Procollagen III N-terminal peptide (PIIINP) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
All the antibodies and antigens for Liver Diseases/Fibrosis test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of Liver Diseases/Fibrosis.
Product Description
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Antigen & Antibody Name
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Anti-human Human PIIINP mouse monoclonal antibody (mAb)
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Expression platform
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Hybridoma
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Isotypes
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Mouse IgG
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Bioactivity validation
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Human Procollagen III N-terminal peptide (PIIINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Procollagen III N-terminal peptide (PIIINP) antibodies in PIIINP level test of Liver diseases (liver fibrosis and cirrhosis) and related syndrome evaluation.
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Tag
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mFc
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Products description
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Anti-human Human PIIINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Procollagen III N-terminal peptide (PIIINP) antibodies.
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Purity
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Purity: ≥95% (SDS-PAGE)
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Application
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ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
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Formulation
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Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
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Storage
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Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No.
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GMP-PIIINP-Ab
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Product Name
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Expression platform
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Bioactivity validation
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Products description
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Diagnostic antibodies and antigens for infectious disease testing including HIV/AIDS, HCV, Influenza A/B, Syphilis, Helicobacter pylori, HSV-1/2, CMV, rubella virus, toxoplasma.
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction.
Genemedi produces core diagnostic ingredients for test of infectious diseases and related syndrome.
GeneMedi offers paired diagnostics grade antibodies (monoclonal antibody,mab)and antigens for infectious disease rapid test kit including infection of HIV/AIDS,Hepatitis C virus(HCV), Influenza A/B,Treponema Pallidum caused Syphilis,Helicobacter pylori (H. pylori) Bacteria, Herpes simplex virus 1/2(HSV-1/HSV-2),Cytomegalovirus (CMV),rubella virus,toxoplasma gondii and so on.
All the antibodies of inflammation and CRS test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibody can act as a capture antibody and detection antibody.
