mouse Cxcr4 AAV plasmid
Cat:pGMAAV000046
Availability:3-7 business days
Description
Catalog ID
pGMAAV000046
Gene Name
Cxcr4
Product Name
mouse Cxcr4 AAV plasmid
Accession Number
NM_009911.3
Gene ID
12767
Species
mouse
Product Type
AAV plasmid
Insert Length
1080
Gene Alias
CD184; LESTR; Sdf1r; CXC-R4; CXCR-4; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1
Fluorescent Label
GFP
Fusion Tag
no tag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Maker
Regulation
overexpression
