rat Syt11 AAV plasmid
Cat:pGMAAV000086
Availability:3-7 business days
Description
Catalog ID
pGMAAV000086
Gene Name
Syt11
Product Name
rat Syt11 AAV plasmid
Accession Number
NM_031667
Gene ID
60568
Species
rat
Product Type
AAV plasmid
Insert Length
1290
Gene Alias
Predicted to enable several functions, including beta-tubulin binding activity; phosphatidylserine binding activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of cellular component organization and negative regulation of dopamine secretion. Located in several cellular components, including inhibitory synapse; presynaptic active zone membrane; and synaptic vesicle. Is active in Schaffer collateral – CA1 synapse and postsynapse. Is integral component of presynaptic active zone membrane and integral component of synaptic vesicle membrane. Orthologous to human SYT11 (synaptotagmin 11). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Maker
Regulation
overexpression
