mouse Hpca AAV plasmid
Cat:pGMAAV000108
Availability:3-7 business days
Description
Catalog ID
pGMAAV000108
Gene Name
Hpca
Product Name
mouse Hpca AAV plasmid
Accession Number
NM_001130419.2
Gene ID
15444
Species
mouse
Product Type
AAV plasmid
Insert Length
582
Gene Alias
Predicted to enable several functions, including actin binding activity; calcium ion binding activity; and identical protein binding activity. Acts upstream of or within inner ear development. Predicted to be located in several cellular components, including dendrite; neuronal cell body membrane; and perikaryon. Predicted to be extrinsic component of membrane. Is expressed in ganglia and telencephalon. Human ortholog(s) of this gene implicated in torsion dystonia 2. Orthologous to human HPCA (hippocalcin). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008]
Maker
Regulation
overexpression
