mouse Aqp5 AAV plasmid

Cat:pGMAAV000118
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Description

Catalog ID

pGMAAV000118

Gene Name

Aqp5

Product Name

mouse Aqp5 AAV plasmid

Accession Number

NM_009701.4

Gene ID

11830

Species

mouse

Product Type

AAV plasmid

Insert Length

798

Gene Alias

Predicted to enable identical protein binding activity and water channel activity. Acts upstream of or within camera-type eye morphogenesis; saliva secretion; and water transport. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and microvillus. Is expressed in early conceptus; lung; olfactory epithelium; oocyte; and salivary gland. Human ortholog(s) of this gene implicated in Bothnian type palmoplantar keratoderma. Orthologous to human AQP5 (aquaporin 5). [provided by Alliance of Genome Resources, Apr 2022]

Fluorescent Label

GFP

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

Aquaporin 5 (AQP5) is a water channel protein.  Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]

Maker

Regulation

overexpression