mouse Aqp5 AAV plasmid
Cat:pGMAAV000118
Description
Catalog ID
pGMAAV000118
Gene Name
Aqp5
Product Name
mouse Aqp5 AAV plasmid
Accession Number
NM_009701.4
Gene ID
11830
Species
mouse
Product Type
AAV plasmid
Insert Length
798
Gene Alias
Predicted to enable identical protein binding activity and water channel activity. Acts upstream of or within camera-type eye morphogenesis; saliva secretion; and water transport. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and microvillus. Is expressed in early conceptus; lung; olfactory epithelium; oocyte; and salivary gland. Human ortholog(s) of this gene implicated in Bothnian type palmoplantar keratoderma. Orthologous to human AQP5 (aquaporin 5). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Maker
Regulation
overexpression