house mouse Ptges AAV plasmid
Cat:pGMAAV000190
Availability:3-7 business days
Description
Catalog ID
pGMAAV000190
Gene Name
Ptges
Product Name
house mouse Ptges AAV plasmid
Accession Number
NM_022415.3
Gene ID
64292
Species
house mouse
Product Type
AAV plasmid
Insert Length
462
Gene Alias
Pges; mPGES; mPGES-1; D2Ertd369e; 2410099E23Rik
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Maker
Regulation
overexpression
