Norway rat Tbx20 AAV plasmid
Cat:pGMAAV000321
Availability:3-7 business days
Description
Catalog ID
pGMAAV000321
Gene Name
Tbx20
Product Name
Norway rat Tbx20 AAV plasmid
Accession Number
NM_001108132.1
Gene ID
315497
Species
Norway rat
Product Type
AAV plasmid
Insert Length
897
Gene Alias
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including circulatory system development; positive regulation of cardiac muscle cell proliferation; and visceral motor neuron differentiation. Predicted to act upstream of or within several processes, including circulatory system development; negative regulation of SMAD protein complex assembly; and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in atrial heart septal defect 4. Orthologous to human TBX20 (T-box transcription factor 20). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Maker
Regulation
overexpression
