human SETDB2 AAV plasmid
Cat:pGMAAV000322
Description
Catalog ID
pGMAAV000322
Gene Name
SETDB2
Product Name
human SETDB2 AAV plasmid
Accession Number
NM_031915
Gene ID
83852
Species
human
Product Type
AAV plasmid
Insert Length
2160
Gene Alias
C13orf4;CLLD8;CLLL8;KMT1F
Fluorescent Label
Null
Fusion Tag
Null
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Maker
Regulation
overexpression