Norway rat Steap4 AAV plasmid
Cat:pGMAAV000369
Availability:3-7 business days
Description
Catalog ID
pGMAAV000369
Gene Name
Steap4
Product Name
Norway rat Steap4 AAV plasmid
Accession Number
NM_001044265.1
Gene ID
499991
Species
Norway rat
Product Type
AAV plasmid
Insert Length
1413
Gene Alias
Predicted to enable several functions, including FAD binding activity; heme binding activity; and oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor. Predicted to be involved in copper ion import; fat cell differentiation; and protein homotrimerization. Predicted to act upstream of or within iron import into cell. Predicted to be located in nucleoplasm. Predicted to be integral component of membrane. Predicted to be active in endosome and plasma membrane. Orthologous to human STEAP4 (STEAP4 metalloreductase). [provided by Alliance of Genome Resources, Apr 2022]
Fluorescent Label
ZsGreen
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Maker
Regulation
overexpression
