Cat:pGMAD000047
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU
pGMAD000047
Categories adv, ADV plasmid, Gene Therapy, orf
Availability:3-7 business days
Description
Catalog ID
pGMAD000047
Gene Name
Nfkbia
Product Name
Accession Number
NM_001105720.2
Gene ID
25493
Species
rat
Product Type
Adenovirus plasmid
Insert Length
945
Gene Alias
RL/IF-1
Fluorescent Label
null
Fusion Tag
null
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Maker
null
Regulation
overexpression