Cat:pGMAD000299
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU
pGMAD000299
Categories adv, ADV plasmid, Gene Therapy, orf
Availability:3-7 business days
Description
Catalog ID
pGMAD000299
Gene Name
Spen
Product Name
Accession Number
NM_019763.2
Gene ID
56381
Species
mouse
Product Type
Adenovirus plasmid
Insert Length
10932
Gene Alias
Mint; mKIAA0929
Fluorescent Label
GFP
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
Maker
GFP
Regulation
overexpression