Since 1975, monoclonal antibodies have been successfully used for the diagnosis and therapeutics. In 1993, heavy-chain-only antibodies which bind to antigens was discovered in camelids. The variable domain of heavy chain antibody (VHH) was called as nanobodies and it was anticipated as the better therapeutic antibodies in future due to its high stability, refoldability, and manipulable characteristics. VHH has also been effectively used for the diagnosis, bioimaging, immunoassay and affinity purification.
View the Knowledge base of Tandem VHH/ Nanobody(single domain antibody):
– Tandem VHH/Nanobody (single domain antibody): Structure, Production, Application and Products
– Tandem VHH/Nanobody (single domain antibody) – Introduction
– Structure and Physicochemical Features of Nanobody (single domain antibody)
– Nanobody (single domain antibody) production
– Application of nanobodies (single domain antibodies)
– Advantages and limitation of Nanobodies (single domain antibodies)
– GeneMedi’s products list of Nanobodies (single domain antibodies)